LGALS3 His Recombinant Protein
Produktgrößen
25 µg
£528,00
32-1223-25UG
Über dieses Produkt
- SKU:
- 32-1223
- Zusätzliche Namen:
- Galectin-3||GAL3||MAC2||CBP35||GALB||GALIG||LGALS2||LGALS3||Galactose-specific lectin 3||Mac-2 antigen||IgE-binding protein||35 kDa lectin||Carbohydrate-binding protein 35||CBP 35||Laminin-binding protein||Lectin L-29||L-31||Galactoside-binding prote
- Weitere Details:
- Source : Escherichia Coli. LGALS3 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 270 amino acids (1-250 a.a.) and having a molecular mass of 28.3 kDa. The LGALS3 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Galectin-3 mediates with the alpha-3; beta-1 integrin the stimulation by cspg4 of endothelial cells migration. Galectin-3 plays an necessary part during the acquisition of vasculogenic mimicry and angiogenic properties associated with melanoma progression. LGALS3 overexpression is highly expressed in early stages of papillary carcinoma; and its expression intensity declines during tumor progression. Serum levels of LGALS3 are high in patients with thyroid malignancy but there is considerable overlap in serum LGALS3 concentrations between those with benign and malignant nodular thyroid disease. LGLAS3 takes part as an immune regulator to inhibit T-cell immune responses and promote tumor growth; as a result providing a new mechanism for tumor immune tolerance.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg