FGF 23 His Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1201-10UG
Über dieses Produkt
- SKU:
- 32-1201
- Zusätzliche Namen:
- Tumor-derived hypophosphatemia-inducing factor||HYPF||ADHR||HPDR2||PHPTC||FGF23||FGF-23||Fibroblast Growth Factor-23.
- Weitere Details:
- Source : Escherichia Coli. Fibroblast Growth Factor-23 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain expressed with a -6xHis tag containing a total of 257 amino acids (251 a.a. FGF23+ 6 a.a. His tag) and having a molecular mass of 28629.5 Dalton. The FGF-23 is and purified by chromatographic techniques. FGF-23 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth and invasion. FGF-23 inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR); an inherited phosphate wasting disorder. Abnormally high level expression of FGF23 was found in oncogenic hypophosphatemic osteomalacia (OHO); a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations FGF23 have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.
- Aufreinigung:
- Greater than 90.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Fibroblast Growth Factor 23 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution FGF-23 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg