EMAP Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1142-20UG
Über dieses Produkt
- SKU:
- 32-1142
- Zusätzliche Namen:
- AIMP1||EMAP2||EMAP-2||EMAPII||SCYE1||Multisynthetase complex auxiliary component p43||Endothelial monocyte-activating polypeptide 2||EMAP-II||p43.
- Weitere Details:
- Source : Escherichia Coli. EMAP-II Recombinant Human produced in E.Coli is a single; non-glycosylated polypeptide chain containing 166 amino acids and having a molecular mass of 18.3 kDa. The EMAP-II is purified by proprietary chromatographic techniques. EMAP-II also called SCYE1 is a tumor derived cytokine that plays a role in a wide variety of activities on endothelial cells; monocytes and neutrophils. EMAP-II inhibits endothelial cell proliferation; vasculogenesis; neovessel formation; and can induce apoptosis. It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils. EMAP-II clinical value is inhibiting angiogenesis of vascular beds and suppressing the growth of primary and secondary tumors with no affect to normal tissues. SCYE1is specifically induced by apoptosis; and it is involved in the control of angiogenesis; inflammation; and wound healing. The release of this SCYE1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit; which is associated with the multi-tRNA synthetase complex; and it modulates aminoacylation activity of tRNA synthetase in normal cells. EMAP-2 plays a role in in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
- Aufreinigung:
- Greater than 98.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized EMAP-II although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution EMAP-II should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg