k9Clusterin HEK Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1052-10UG
Über dieses Produkt
- SKU:
- 32-1052
- Zusätzliche Namen:
- CLI||AAG4||KUB1||SGP2||SGP-2||SP-40||TRPM2||MGC24903||Clusterin||Glycoprotein 80||Gp80||CLU.
- Weitere Details:
- Source : Human Embryonic Kidney 293 Cells. Clusterin Canine Recombinant produced in HEK293 cells is a glycosylated; Polypeptide chain containing 436 amino acids and having a molecular mass of 50.72 kDa. The protein is fused with 13 amino acid Flag tag at N-Terminus.The Apolipoprotein-J Canine is purified by proprietary chromatographic techniques. Clusterin mRNA and Clusterin protein are shown to increase with androgen treatment. Binding of clusterin to the LDL-Receptor plays a role in the pathogenesis of membranous glomerulonephritis. Clusterin is down regulated in CaP in association with matched benign controls. Clusterin is involved in cellular senescence and tumorigenesis. Clusterin is involved in photo-oxidative cell death pathway. Clusterin is a functional tumor marker for the diagnosis of pediatric large cell lymphoma. Clusterin is activated in low pH. Clusterin is involved in the inhibition of NF-kappaB signaling through stabilization of IkappaBs thus results in suppression of tumor cell motility. N-terminal deletion of clusterin is vital for its alterations of biogenesis in esophageal squamous cell carcinoma.
- Aufreinigung:
- Greater than 95% as determined by SDS PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg