Anti-Human CD123 PerCP Mab (Clone:6H6)
Produktgrößen
100 tests
£620,00
30-2885-100TESTS
Über dieses Produkt
- SKU:
- 30-2885
- Zusätzliche Namen:
- IL3RA; MGC34174; hIL-3Ra
- translate.label.attr.clone:
- 6H6
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity : The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha); a 60-70 kDa transmembrane protein expressed by myeloid precursors; megakaryocytes; macrophages; dendritic cells; mast cells; basophils; and some B cells. This antibody does not inhibit IL-3 binding to its receptor. CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131); which is shared with other receptors. CD123 interacts with IL-3 specifically; but with low affinity; and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling; but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
- Host:
- Mouse
- Immunogen:
- IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatograp
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
