Anti-Human SIGLEC10 Mab (Clone: 5G6 )
Produktgrößen
0.1 mg
£541,00
30-2868-0.1MG
Über dieses Produkt
- SKU:
- 30-2868
- Zusätzliche Namen:
- PRO940; SGL2; sialic acid binding Ig like lectin 10
- translate.label.attr.clone:
- 5G6
- Klonalität:
- Monoclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Specificity : The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10; a sialic acid-binding lectin expressed on subsets of human leucocytes. SIGLEC10 is a CD33-related receptor of sialoglycans; expressed on eosinophils; monocytes; a subpopulation of NK cells; and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor; which binds to VAP-1; a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24; a marker of poorer prognosis in carcinomas.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg