APC Conjugated Anti-Human SIGLEC10 Mab (Clone: 5G6 )
Produktgrößen
100 Tests
£620,00
30-2868-AC-100TESTS
Über dieses Produkt
- SKU:
- 30-2868-AC
- Zusätzliche Namen:
- PRO940; SGL2; sialic acid binding Ig like lectin 10
- translate.label.attr.clone:
- 5G6
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- Specificity : The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10; a sialic acid-binding lectin expressed on subsets of human leucocytes. SIGLEC10 is a CD33-related receptor of sialoglycans; expressed on eosinophils; monocytes; a subpopulation of NK cells; and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor; which binds to VAP-1; a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24; a marker of poorer prognosis in carcinomas.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- urified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze. Avoid exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:30-2868-AC 1.jpeg
