Anti-Human CD39 FITC MAb (Clone: TU66)
Produktgrößen
100 tests
£581,00
30-2847-100TESTS
Über dieses Produkt
- SKU:
- 30-2847
- Zusätzliche Namen:
- ETDH1; LCAA; Ecto-ATPase 1; Ecto-apyrase; ENTPD1
- translate.label.attr.clone:
- TU66
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- Specificity: The mouse monoclonal antibody TU66 recognizes an extracellular epitope of CD39; a 78 kDa cell surface enzyme expressed by regulatory T cells; mantle zone B cells; activated T cells; NK cells; macrophages; dendritic cells; neurons; endothelial cells and platelets. CD39; also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1); is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP. Inhibition of its enzymatic activity may confer anticancer benefits. The formation of oligomers in the plasma membrane is essential for enzyme activity. It is expressed on Treg cells; and in other cell types; such as mantle zone B cells; activated T cells; NK cells; macrophages; dendritic cells; neurons; endothelial cells and platelets. Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses. In the nervous system; it regulates purinergic neurotransmission.
- Host:
- Mouse
- Isotyp:
- Mouse IgG2b kappa
- Aufreinigung:
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
