Anti-Hu CD11b Purified
Produktgrößen
0.1 mg
£532,00
30-2828-0.1MG
Über dieses Produkt
- SKU:
- 30-2828
- Zusätzliche Namen:
- integrin subunit alpha M Mac-1; Integrin alpha M; ITGAM; CR3A; MO1A; MAC1A
- translate.label.attr.clone:
- ICRF44
- Klonalität:
- Monoclonal
- Weitere Details:
- CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1; CR3) is highly expressed on NK cells; neutrophils; monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes; macrophages and granulocytes; facilitating their diapedesis; as well as it mediates the uptake of complement coated particles; serving as a receptor for the iC3b fragment of the third complement component.Specificity :The mouse monoclonal antibody ICRF44 recognizes an extracellular epitope of CD11b (Mac-1alpha); a 165-170 kDa type 1 transmembrane protein mainly expressed on monocytes; granulocytes and NK-cells.
- Format:
- Purified
- Immunogen:
- Rheumatoid synovial cells and human monocytes.
- Aufreinigung:
- Purified by protein-A affinity chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php