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Anti-Hu CD15 (Clone W6D3) PE Conjugated

Produktgrößen
100 Tests
£649,00
30-2825PE-100TESTS
Über dieses Produkt
SKU:
30-2825PE
Zusätzliche Namen:
Lewis x Blood Group antigen; Le(x); SSEA-1; 3-fucosyl-N-acetyllactosamine
translate.label.attr.clone:
W6D3
Klonalität:
Monoclonal
Konjugat:
PE
Weitere Details:
CD15 (Lewis x); also known as stage specific embryonic antigen-1 (SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids; glycoproteins and proteoglycans of various cell types; e.g. granulocytes; mast cells; monocytes; macrophages; cells of gastric mucosa; nervous system or various tumour cells. There are several structural relatives of Lewis x; e.g. sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation; based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease. Specificity :Mouse monoclonal antibody W6D3 recognizes CD15 in nonterminal position on extracellular glycoproteins. CD15 (a cell membrane 3-fucosyl-N-acetyllactosamine; 3-FAL) is strongly expressed on granulocytes; monocytes; macrophages; mast cells; it is also present on Langerhans cells and some myeloid precursors cells. This is a non-IgM anti-CD15 antibody.
Immunogen:
WERI-RB-1 retinoblastoma cell line
Aufreinigung:
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Conjugated Protein
Figure 2: Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD15 (W6D3) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
Figure 2: Separation of human neutrophil granulocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD15 (W6D3) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).