Anti-Hu CD15 (Clone W6D3) Purified
Produktgrößen
0.1 mg
£541,00
30-2825-0.1MG
Über dieses Produkt
- SKU:
- 30-2825
- Zusätzliche Namen:
- Lewis x Blood Group antigen; Le(x); SSEA-1; 3-fucosyl-N-acetyllactosamine
- translate.label.attr.clone:
- W6D3
- Klonalität:
- Monoclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- CD15 (Lewis x); also known as stage specific embryonic antigen-1 (SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids; glycoproteins and proteoglycans of various cell types; e.g. granulocytes; mast cells; monocytes; macrophages; cells of gastric mucosa; nervous system or various tumour cells. There are several structural relatives of Lewis x; e.g. sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation; based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease. Specificity :Mouse monoclonal antibody W6D3 recognizes CD15 in nonterminal position on extracellular glycoproteins. CD15 (a cell membrane 3-fucosyl-N-acetyllactosamine; 3-FAL) is strongly expressed on granulocytes; monocytes; macrophages; mast cells; it is also present on Langerhans cells and some myeloid precursors cells. This is a non-IgM anti-CD15 antibody.
- Format:
- Purified
- Immunogen:
- WERI-RB-1 retinoblastoma cell line
- Aufreinigung:
- Purified by protein-A affinity chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:30-2825 1.jpeg
