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Antikörper

Anti-Hu CD272 Purified

Produktgrößen
0.1 mg
£541,00
30-2811-0.1MG
Über dieses Produkt
SKU:
30-2811
Zusätzliche Namen:
B and T lymphocyte associated BTLA1
translate.label.attr.clone:
MIH26
Klonalität:
Monoclonal
Weitere Details:
CD272; a type I transmembrane glycoprotein; contains in its intracellular domain two ITIM sequences; which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes; NK cells; dendritic cells; and macrophages; and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.Specificity :The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272; a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
Format:
Purified
Immunogen:
cells transfected with human CD272
Aufreinigung:
Purified by protein-A affinity chromatography.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody