Anti-Hu CD294 Purified
Produktgrößen
0.1 mg
£541,00
30-2810-0.1MG
Über dieses Produkt
- SKU:
- 30-2810
- Zusätzliche Namen:
- prostaglandin D2 receptor 2 DP2; PTGDR2; DL1R; CRTH2; GPR44
- translate.label.attr.clone:
- BM16
- Klonalität:
- Monoclonal
- Weitere Details:
- CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells; but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils; basophils; and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut; heart; and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C.Specificity :The rat monoclonal antibody BM16 recognizes an extracellular epitope of CD294 / CRTH2 (prostaglandin D2 receptor 2); a G-protein-coupled seven-transmembrane protein expressed on Th2 cells; peripheral blood basophils and eosinophils.
- Format:
- Purified
- Immunogen:
- Human CD294 transfected rat cell line TART/B19-12.10
- Aufreinigung:
- Purified by protein-G affinity chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php