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Antikörper

Anti-Hu CD367 Purified

Produktgrößen
0.1 mg
£541,00
30-2786-0.1MG
Über dieses Produkt
SKU:
30-2786
Zusätzliche Namen:
C-type lectin domain family 4 member A DCIR; CLEC4A; LLIR
translate.label.attr.clone:
9E8
Klonalität:
Monoclonal
Weitere Details:
CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose; fucose; and weakly also to N-acetylglucosamine. It is expressed on dendritic cells; macrophages; monocytes; B cells; and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering; it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.Specificity :The mouse monoclonal antibody 9E8 recognizes an extracellular epitope of human CD367; a type II transmembrane protein of C-lectin family; expressed mainly on antigen presenting cells.
Format:
Purified
Immunogen:
CD367 ectodomain fused with human Fc
Aufreinigung:
Purified by protein-A affinity chromatography.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody