Anti-Ms CD8a FITC
Produktgrößen
0.1 mg
£502,00
30-2749-0.1MG
Über dieses Produkt
- SKU:
- 30-2749
- Zusätzliche Namen:
- CD8a molecule Ly-2; Ly-B; Ly-35; Lyt-2; BB154331
- translate.label.attr.clone:
- 53-6.7
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- The CD8a (CD8 alpha) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells; intraepithelial lymphocytes; NK cells; macrophages and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8; thereby affecting the functional diversity of the TCR signaling. Specificity :The rat monoclonal antibody 53-6.7 recognizes an extracellular epitope of murine CD8a (32-34 kDa; alpha chain of the CD8 antigen).
- Immunogen:
- Murine spleen cells
- Aufreinigung:
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php