Anti-FoxP3 Purified
Produktgrößen
0.1 mg
£610,00
30-2739-0.1MG
Über dieses Produkt
- SKU:
- 30-2739
- Zusätzliche Namen:
- forkhead box P3 Scurfin; JM2; AIID; IPEX; PIDX; XPID; DIETER
- translate.label.attr.clone:
- 3G3
- Klonalität:
- Monoclonal
- Weitere Details:
- FoxP3 (forkhead box protein 3); a highly conserved forkhead/winged-helix transcription factor; plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice; and in human the IPEX syndrome (immune dysfunction; polyendocrinopathy; enteropathy; X-linked syndrome); also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome.Specificity :The mouse monoclonal antibody 3G3 recognizes N-terminal region of FoxP3; a 47-55 kDa transcription factor (intracellular antigen); which is the master regulator in the development and function of regulatory T cells.
- Format:
- Purified
- Immunogen:
- Full-length His-tagged recombinant murine FoxP3
- Aufreinigung:
- Purified by protein-A affinity chromatography.
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php