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Antikörper

Anti-Hu Granzyme A Purified

Produktgrößen
0.1 mg
£541,00
30-2737-0.1MG
Über dieses Produkt
SKU:
30-2737
Zusätzliche Namen:
Granzyme A HFSP; CTLA3; GrA
translate.label.attr.clone:
CB9
Klonalität:
Monoclonal
Weitere Details:
Granzyme A is a serine protease expressed in the cytoplasmic granules of T cells and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Similarly to granzyme B; granzyme A acts to destroy the target cells by proteolysis of their particular components. In case of granzyme A the targets are e.g. APEX1 (it destroys its oxidative repair activity); and nucleosome assembly protein SET (it disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA).Specificity :The mouse monoclonal CB9 recognizes granzyme A; a 28 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
Format:
Purified
Immunogen:
Full length human granzyme A
Aufreinigung:
Purified by protein-A affinity chromatography.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody