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Anti-Hu Galectin-9 Purified (clone:9M1-3)

Produktgrößen
0.1 mg
£541,00
30-2698-0.1MG
Über dieses Produkt
SKU:
30-2698
Zusätzliche Namen:
HUAT; LGalS9A; LEG9
translate.label.attr.clone:
9M1-3
Klonalität:
Monoclonal
Konjugat:
Unconjugated
Weitere Details:
Galectin-9 is a glycan-binding protein; which is expressed in three main isoforms of 49 aa; 27 aa; and 15 aa. It can be detected on the cell surface; as well as intracellularly; or in a secreted form. On the cell surface; galectin-9 plays roles in contacts with other cells and with extracellular matrix. It is expressed on multiple cell types; but mainly on Treg cells; activated Th cells and some cancers. Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions. Massive and inadequate production of galectin-9; associated with some viral infections or cancers; can counteract immune reactions to these illnesses. High levels of galectin-9 expression lead to poor prognosis of cancer patients. Galectin-9 is a glycan-binding protein; which is expressed in three main isoforms of 49 aa; 27 aa; and 15 aa. It can be detected on the cell surface; as well as intracellularly; or in a secreted form. On the cell surface; galectin-9 plays roles in contacts with other cells and with extracellular matrix. It is expressed on multiple cell types; but mainly on Treg cells; activated Th cells and some cancers. Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions. Massive and inadequate production of galectin-9; associated with some viral infections or cancers; can counteract immune reactions to these illnesses. High levels of galectin-9 expression lead to poor prognosis of cancer patients. Specificity : The mouse monoclonal antibody 9M1-3 recognizes an epitope within C terminus of human galectin-9; a glycan-binding protein expressed mainly on activated Th cells and FoxP3+ Treg cells.
Format:
Purified
Host:
Mouse
Immunogen:
recombinant M-type splicing variant of human galectin 9
Isotyp:
Mouse IgG1 kappa
Aufreinigung:
Purified by protein-A affinity chromatography.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze. Phosphate buffered saline (PBS); pH 7.4; 15 mM sodium azide.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Lectins
  • Datenblatt des Herstellers:1.jpg