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Antikörper

Anti-Human CD133 APC (Clone : W6B3C1)

Produktgrößen
100 tests
£620,00
30-2657-100TESTS
Über dieses Produkt
SKU:
30-2657
Zusätzliche Namen:
Prominin 1; PROM1; AC133; PROML1; STGD4;prominin 1
translate.label.attr.clone:
W6B3C1
Klonalität:
Monoclonal
Konjugat:
APC
Weitere Details:
CD133 (prominin 1) is a 5-transmembrane glycoprotein with extracellular N- and intracellular C-terminus. CD133 function remains to be elucidated; but it can be used as a cancer stem cell marker. Its expression pattern in progenitor cells is similar to CD34; i.e. on hematopoietic stem cells in bone marrow; cord blood; neural stem cells; retinoblastoma; or endothelial precursor cells (not mature endothelial cells). It is being used for identification and isolation of hematopoietic stem cells; including isolation for stem cell transplantation. Expression of CD133 correlates with differentiation of human colon cancer cells.Specificity : The mouse monoclonal antibody W6B3C1 recognizes the extracellular glycosylated epitope 1 on human CD133 (CD133/1); a 120 kDa glycoprotein of prominin family; expressed e.g. on progenitor cells. This antibody is important for identification of stem cells and tumor cells.
Immunogen:
WERI-RB-1 retinoblastoma cell line
Isotyp:
Mouse IgG1
Aufreinigung:
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Figure 2 : Flow cytometry multicolor surface staining of human bone marrow cells stained using anti-human CD133 (W6B3C1) APC antibody (10 µl reagent per milion cells in 100 µl of cell suspension) and anti-human CD34 (581) PE antibody (20 µl reagent per milion cells in 100 µl of cell suspension).
Figure 3 :Separation of human CD133 positive CD34 positive stem cells (red-filled) from CD133 negative CD34 negative cells (black-dashed) in flow cytometry analysis (surface staining) of human bone marrow cells stained using anti-human CD133 (W6B3C1) APC antibody (10 µl reagent per milion cells in 100 µl of cell suspension).
Figure 3 :Separation of human CD133 positive CD34 positive stem cells (red-filled) from CD133 negative CD34 negative cells (black-dashed) in flow cytometry analysis (surface staining) of human bone marrow cells stained using anti-human CD133 (W6B3C1) APC antibody (10 µl reagent per milion cells in 100 µl of cell suspension).