Anti-Human CD143 PE (Clone : 5-369)
Produktgrößen
100 tests
£620,00
30-2653-100TESTS
Über dieses Produkt
- SKU:
- 30-2653
- Zusätzliche Namen:
- DCP; ACE1; DCP1; carboxycathepsin; kininase II; peptidase P; peptidyl dipeptidase 1;angiotensin I converting enzyme
- translate.label.attr.clone:
- 5-369
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD143; also known as ACE (angiotensin-converting enzyme); carboxycathepsin; kininase II; peptidase P; or peptidyl dipeptidase 1; is a transmembrane zinc metallopeptidase catalyzing the conversion of angiotensin I into the physiologically active angiotensin II; which is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified; and two most abundant spliced variants encode the somatic form and the testicular form; that are equally active. CD143 is expressed mainly on endothelial cells; but it can be found also e.g. on activated macrophages and histiocytes.Specificity : The mouse monoclonal antibody 5-369 recognizes an extracellular epitope of CD143; a 171 kDa type I transmembrane glycoprotein with metallopeptidase activity; expressed mainly on endothelial cells.
- Immunogen:
- dendritic cells
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php