Anti-Human CD15 PE (Clone : MMA)
Produktgrößen
100 tests
£620,00
30-2650-100TESTS
Über dieses Produkt
- SKU:
- 30-2650
- Zusätzliche Namen:
- Lewis x Blood Group antigen; Le(x); SSEA-1; 3-fucosyl-N-acetyllactosamine;
- translate.label.attr.clone:
- MMA
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD15 (Lewis X; Le(x); stage specific embryonic antigen-1; SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids; glycoproteins and proteoglycans of various cell types; e.g. granulocytes; mast cells; monocytes; macrophages; cells of gastric mucosa; nervous system or various tumour cells. There are several variants of Lewis x; such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation; based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.Specificity : The mouse monoclonal antibody MMA reacts with an extracellular epitope of CD15; a cell membrane 3-fucosyl-N-acetyllactosamine (3-FAL) strongly expressed on granulocytes; monocytes; macrophages; mast cells; it is also present on Langerhans cells and some myeloid precursors cells. This antibody is a superior reagent for identifying of Hodgkin´s lymphoma.
- Immunogen:
- U937 histiocytic lymphoma cells
- Isotyp:
- Mouse IgM kappa
- Aufreinigung:
- The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg