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Antikörper

Anti-Human CD158d Low Endotoxin Antibody (Clone : mAb#33)

Produktgrößen
0.1 mg
£581,00
30-2646-0.1MG
Über dieses Produkt
SKU:
30-2646
Zusätzliche Namen:
KIR2DL4; KIR103AS; 103AS; 15.212;killer cell immunoglobulin like receptor; two Ig d
translate.label.attr.clone:
mAb#33
Klonalität:
Monoclonal
Weitere Details:
CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM; suggesting inhibitory function; but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells; but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-γ secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G. Specificity : The mouse monoclonal antibody mAb#33 (also known as mAb 33 or 33) recognizes extracellular portion of CD158d / KIR2DL4; a 45 kDa NK cell marker. Cell surface expression and function of CD158d / KIR2DL4 depends on genotype of particular individuals.
Format:
Low Endotoxin
Immunogen:
NK3.3 cells and KIR2DL4-Ig fusion protein
Isotyp:
Mouse IgG1 kappa
Aufreinigung:
Purified by protein-A affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody