Anti-Human CD172b PE (Clone : B4B6)
Produktgrößen
100 tests
£620,00
30-2631-100TESTS
Über dieses Produkt
- SKU:
- 30-2631
- Zusätzliche Namen:
- SIRPB1;signal regulatory protein beta 1
- translate.label.attr.clone:
- B4B6
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD172b; the signal-regulatory protein beta (SIRP beta) is a disulfide-linked homodimer expressed on myeloid cells including monocytes and dendritic cells. Similarly to CD172a; it serves as a negative regulator of tyrosine kinase-coupled signaling processes. Unlike CD172a; the CD172b protein does not possess the cytoplasmic domain; but instead its transmembrane domain can interact with another transmembrane protein DAP-12; which contains ITAM sequences in its intracellular domain and links CD172b to the downstream signaling molecules. The result is e.g. regulation of neutrophil transepithelial migration.Specificity : The mouse monoclonal antibody B4B6 recognizes an extracellular epitope of CD172b; an approximately 50 kDa transmembrane glycoprotein expressed on myeloid cells.
- Immunogen:
- NIH-3T3 cells transfected with human CD172b
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg