Anti-Human CD21 PerCP (Clone : LT21)
Produktgrößen
100 tests
£620,00
30-2621-100TESTS
Über dieses Produkt
- SKU:
- 30-2621
- Zusätzliche Namen:
- CR2; C3DR2; CVID7; SLEB9;complement C3d receptor 2
- translate.label.attr.clone:
- LT21
- Klonalität:
- Monoclonal
- Konjugat:
- PerCP
- Weitere Details:
- CD21 (complement receptor 2; CR2) binds C3 complement fragments; especially its breakdown fragments; which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes; survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.Specificity : The antibody LT21 reacts with an extracellular epitope of CD21 (CR2); a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes; follicular dendritic cells; some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
- Immunogen:
- IM9 human B-lymphoblastoid cell line
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with PerCP under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
