Anti-Human CD253 APC (Clone : 2E5)
Produktgrößen
0.1 mg
£620,00
30-2613-0.1MG
Über dieses Produkt
- SKU:
- 30-2613
- Zusätzliche Namen:
- TRAIL; Apo-2 ligand; Apo-2L; TNFSF10; APO2L; TNLG6A;TNF superfamily member 10
- translate.label.attr.clone:
- 2E5
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand); also called Apo2; is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells; but not in normal cells. TRAIL-induced apotosis; is achieved through binding to two dealth-signaling receptors; DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).Specificity : The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L); a 21 kDa cytotoxic protein; activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen; lung; prostate and also in many other tissues.
- Immunogen:
- Recombinant soluble fragment (aa 95-281) of human TRAIL.
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php