Anti-Human CD264 APC (Clone : TRAIL-R4-01)
Produktgrößen
0.1 mg
£620,00
30-2608-0.1MG
Über dieses Produkt
- SKU:
- 30-2608
- Zusätzliche Namen:
- TNFRSF10D; DcR2; TRUNDD; TRAILR4;TNF receptor superfamily member 10d
- translate.label.attr.clone:
- TRAIL-R4-01
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- TRAIL-R4 (CD264; TR4; DcR2; TRUNDD); expressed mainly on CD8+ and NK cells; belongs to receptors of TRAIL; a TNF-like membrane toxic protein that induces apoptosis in many tumour cells; but not in normal cells. TRAIL-R4; however; contains partially truncated death domain; thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).Specificity : The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4; a 42 kDa transmembrane protein expressed on various blood cells.
- Immunogen:
- TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
