Anti-Human CD273 APC (Clone : 24F.10C12)
Produktgrößen
100 tests
£620,00
30-2602-100TESTS
Über dieses Produkt
- SKU:
- 30-2602
- Zusätzliche Namen:
- PDCD1LG2; B7DC; Btdc; PDL2; PDCD1L2; bA574F11.2; Butyrophilin; B7-DC;programmed cell death 1 ligand 2
- translate.label.attr.clone:
- 24F.10C12
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD273 / PD-L2 (programmed death ligand-1); also known as B7-DC; is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells; and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279; it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.Specificity : The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC); a 25 kDa type I transmembrane protein expressed by dendritic cells; activated monocytes and T cells; heart; first trimester placenta; lung and liver; as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
- Immunogen:
- human CD273
- Isotyp:
- Mouse IgG2a kappa
- Aufreinigung:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
