Anti-Human CD274 FITC (Clone : 29E.2A3)
Produktgrößen
100 tests
£581,00
30-2601-100TESTS
Über dieses Produkt
- SKU:
- 30-2601
- Zusätzliche Namen:
- B7H1; PDL1; PDCD1L1; PDCD1LG1; PDCD1 ligand 1; B7-H1;CD274 molecule
- translate.label.attr.clone:
- 29E.2A3
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- CD274 / PD-L1 (programmed death ligand-1); also known as B7-H1; is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279; existence of other receptor(s) for CD274 is likely.Specificity : The mouse monoclonal antibody 29E.2A3 recognizes an extracellular epitope of CD274 / PD-L1 (also known as B7-H1); a 40 kDa type I transmembrane protein expressed by dendritic cells; activated T cells; activated monocytes; and in various tissues; above all in heart and skeletal muscle; placenta and lung; and in many cancer cells; including T cell lymphomas; melanomas; and glioblastomas.
- Immunogen:
- Full length human CD274
- Isotyp:
- Mouse IgG2b kappa
- Aufreinigung:
- The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
