Anti-Human CD300a APC (Clone : MEM-260)
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100 tests
£620,00
30-2591-100TESTS
Über dieses Produkt
- SKU:
- 30-2591
- Zusätzliche Namen:
- IRC; CLM-8; IGSF12; CMRF35H;CD300a molecule
- translate.label.attr.clone:
- MEM-260
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD300a (CMRF-35H; IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily; which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells; NK cells; neutrophils; eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5; GM-CSF or eotaxin; as well as supresses mast cell degranulation or NK cell cytotoxic activity.Specificity : The antibody MEM-260 reacts with an extracellular epitope of CD300a; a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes; monocytes; neutrophils; NK cells; mast cells and dendritic cells; 25% of circulating T cells and 15% of circulating B cells.
- Immunogen:
- HPB human acute lymphoid leukemia cell line
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg