Anti-Human CD340 APC (Clone : 24D2)
Produktgrößen
100 tests
£620,00
30-2579-100TESTS
Über dieses Produkt
- SKU:
- 30-2579
- Zusätzliche Namen:
- ERBB2; NEU; NGL; HER2; TKR1; MLN 19;erb-b2 receptor tyrosine kinase 2
- translate.label.attr.clone:
- 24D2
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- The oncoprotein ErbB2/HER2 (human epidermal growth factor receptor 2); also known as Neu or CD340; is a 185 kDa transmembrane tyrosine kinase of cell surface growth factor receptor family. It is present in a wide variety cell types of normal human fetal and adult tissues and is frequently overexpressed in human carcinomas (e.g. in 20-30% cases of breast cancer cells). Activation of ErbB2 triggers intracellular signalling events; which are essential for cell growth and differentiation. In the last 20 years ErbB2 antigen has become very important marker and therapy target in patient care.Specificity : The mouse monoclonal antibody 24D2 recognizes an extracellular epitope of human CD340 (HER-2); a type I transmembrane protein expressed by mesenchymal stem cells; B-lymphoblastic leukemia cells; subsets of C-ALL blasts; and and various types of carcinomas.
- Immunogen:
- NIH-3T3/huCD340 cells
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php