Anti-Human CD36 Biotin (Clone : TR9)
Produktgrößen
0.1 mg
£581,00
30-2574-0.1MG
Über dieses Produkt
- SKU:
- 30-2574
- Zusätzliche Namen:
- GPIIIb; GPIV; PAS-4; FAT; Thrombospondin receptor; PASIV;CD36 molecule
- translate.label.attr.clone:
- TR9
- Klonalität:
- Monoclonal
- Konjugat:
- Biotin
- Weitere Details:
- CD36 (fatty acid translocase; FAT) is an 88 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells; and it is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells; but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4; CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse; CD36 is responsible for gustatory perception of long-chain fatty acids.Specificity : The antibody TR9 reacts with an extracellular epitope of CD36 (GPIIIb); a 85 kDa integral membrane glycoprotein expressed on platelets; macrophages; endothelial cells; early erythroid cells and megakaryocytes. The antibody TR9 cross-blocks binding of FITC-labeled standard antibody OKM5. Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes to target cells).
- Immunogen:
- Platelets
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
