Anti-Human CD51/CD61 Antibody (Clone : 23C6) Biotin Conjugated
Produktgrößen
0.1 mg
£581,00
30-2554-B-0.1MG
Über dieses Produkt
- SKU:
- 30-2554-B
- Zusätzliche Namen:
- VNRA; MSK8; ITGB3; ITGAV; Integrin alpha5beta3; OFA; VR
- translate.label.attr.clone:
- 23C6
- Klonalität:
- Monoclonal
- Konjugat:
- Biotin
- Weitere Details:
- Specificity: The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex; that is expressed mainly on human osteoclasts; but also e.g. on placenta; or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes. Description: CD51/CD61 (integrin alpha5beta3); also known as osteoclast functional antigen; serves as a vitronectin receptor; and binds also to fibronectin; fibrinogen; thrombospondin; osteopontin; collagen; and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts; placenta; and endothelial cells; at lower levels on platelets and macrophages. Specificity : The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex; that is expressed mainly on human osteoclasts; but also e.g. on placenta; or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
- Format:
- Purified
- Immunogen:
- A cell suspension containing osteoclasts from osteoclastomas
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies
- Datenblatt des Herstellers:img1.jpg