Anti-HLA-F PE (Clone : 3D11)
Produktgrößen
0.1 mg
£719,00
30-2519-0.1MG
Über dieses Produkt
- SKU:
- 30-2519
- Zusätzliche Namen:
- CDA12;major histocompatibility complex; class I; F
- translate.label.attr.clone:
- 3D11
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- HLA-F; an MHC class I molecule; is a type I transmembrane protein (heavy chain); which forms heterodimers with beta-2 microglobulin (light chain) and binds to KIR3DS1; KIR3DS4; KIR3DL2; ILT2; ILT4; and TAP. Unlike most other HLA proteins; HLA-F is mainly localized in the endoplasmic reticulum and Golgi apparatus; with only a small amount present on the cell surface in some cell types; surface expression can be induced by cell activation. It is thought to bind a restricted subset of peptides for immune presentation. Multiple transcript variants encoding different isoforms have been found for HLA-F gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site; resulting in a shorter cytoplasmic domain.Specificity : The mouse monoclonal antibody 3D11 recognizes an extracellular epitope of HLA-F; a 42 kDa type I transbembrane protein expressed on B cells; NK cells; monocytes; and T cells; but mainly in the endoplasmic reticulum and Golgi apparatus; only a small amount on the cell surface; where; however; it can be expressed after cell activation.
- Immunogen:
- Inclusion body-derived HLA-F heavy chain
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php