Anti-p21Waf1 Antibody (Clone : WA-1)
Produktgrößen
0.1 mg
£551,00
30-2498-0.1MG
Über dieses Produkt
- SKU:
- 30-2498
- Zusätzliche Namen:
- CDKN1A; CIP1; CAP20;cyclin dependent kinase inhibitor 1A
- translate.label.attr.clone:
- WA-1
- Klonalität:
- Monoclonal
- Weitere Details:
- The tumour suppressor p21Waf1 (Wild-type p53-Activated Fragment 1; also known as Cip1; Cdk interacting protein; or SDI 1) is a cyclin-dependent kinase (Cdk) inhibitor; which is expressed by involvement of p53; Egr-1; AP2; STATs or other transcription factors upon various stimuli resulting in cell cycle arrest. Through its N-terminal domain p21Waf1 inhibits Cdk activity; whereas through the C-terminal domain it inhibits the activity of PCNA (proliferating cell nuclear antigen) to activate DNA replication. Cytosolic location of p21 counteracts its inhibitory activities.Specificity : The antibody WA-1 reacts with p21 protein (Waf1; Cip1; SDI 1; intracellular antigen); a 21 kDa tumour suppressor; which inhibits the activity of cyclin-dependent family kinases and of proliferating cell nuclear antigen.
- Format:
- Purified
- Immunogen:
- Human p21 protein
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies
- Datenblatt des Herstellers:1.jpg
