Anti-CD152 / CTLA4 Monoclonal Antibody (Clone:BNI3)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2396-100TESTS
Über dieses Produkt
- SKU:
- 30-2396
- Zusätzliche Namen:
- CTLA4||CD152
- translate.label.attr.clone:
- BNI3
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD152 / CTLA-4 is a homodimeric transmembrane protein similar to CD28 and binding the same ligands; i.e. CD80 (B7.1) and CD86 (B7.2); but with higher affinity. Unlike CD28 with important costimulating functions; CD152 acts as an important inhibitory receptor essential for modulation of the immune system. CD152 / CTLA-4 becomes transiently expressed on activated T cells and its malfunction can cause autoimmune diseases; such as insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; or thyroid-associated orbitopathy.
- Host:
- Mouse
- Immunogen:
- Human CD152-IgG heavy chain fusion protein
- Isotyp:
- Mouse IgG2a
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg