Anti-CD200 Monoclonal Antibody (Clone:OX-104)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2367-100TESTS
Über dieses Produkt
- SKU:
- 30-2367
- Zusätzliche Namen:
- OX-2 membrane glycoprotein; MOX1; MOX2
- translate.label.attr.clone:
- OX-104
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein; which contains two extracellular immunoglobulin domains; transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells; B and T cell subsets; follicular dendritic cells; keratinocytes; and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production); inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.
- Host:
- Mouse
- Immunogen:
- Human CD200
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg