Anti-CD11b Monoclonal Antibody (Clone:ICRF44)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2332-100TESTS
Über dieses Produkt
- SKU:
- 30-2332
- Zusätzliche Namen:
- ITGAM||CD11B||CR3A
- translate.label.attr.clone:
- ICRF44
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1; CR3) is highly expressed on NK cells; neutrophils; monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes; macrophages and granulocytes; facilitating their diapedesis; as well as it mediates the uptake of complement coated particles; serving as a receptor for the iC3b fragment of the third complement component.
- Host:
- Mouse
- Immunogen:
- Rheumatoid synovial cells and human monocytes.
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg