Anti-CD83 Monoclonal Antibody (Clone:HB15e)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2329-100TESTS
Über dieses Produkt
- SKU:
- 30-2329
- Zusätzliche Namen:
- CD83
- translate.label.attr.clone:
- HB15e
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family. It is expressed on the surface of mature dendritic cells; Langerhans cells in the skin; and interdigitating reticulum cells in the lymphoid tissues. Low expression of CD83 has been reported in activated T and B cells. Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages. CD83 is involved in modulation of antigen presentation. Soluble CD83 has immunoregulatory functions; it is able to down-regulate dendritic cell maturation and stimulation of T cells. In the developing immune system; release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect. Herpes simplex virus; on the other hand; causes CD83 degradation in mature dendritic cells.
- Host:
- Mouse
- Immunogen:
- Human CD83-transfected Cos cells
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg