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Antikörper

Anti-CD16 / FcgammaRIII Monoclonal Antibody (Clone:3G8)-PE Conjugated

Produktgrößen
100 tests
£620,00
30-2300-100TESTS
Über dieses Produkt
SKU:
30-2300
Zusätzliche Namen:
FCGR3A||CD16A||FCG3||FCGR3||IGFR3
translate.label.attr.clone:
3G8
Klonalität:
Monoclonal
Konjugat:
PE
Weitere Details:
CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms - FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes; macrophages; NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated; moreover; with FcepsilonRI-beta subunit. Besides IgG; FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
Host:
Mouse
Immunogen:
Human neutrophils
Isotyp:
Mouse IgG1
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Figure 2: Flow cytometry multicolor surface staining pattern of human lymphocytes using anti-human CD16 (3G8) PE antibody (20 μl reagent / 100 μl of peripheral whole blood) and anti-human CD3 (UCHT1) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Figure 3: Separation of human CD3 negative CD16 positive NK cells (red-filled) from human CD3 positive CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD16 (3G8) PE (20 μl reagent / 100 μl of peripheral whole blood).
Figure 3: Separation of human CD3 negative CD16 positive NK cells (red-filled) from human CD3 positive CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD16 (3G8) PE (20 μl reagent / 100 μl of peripheral whole blood).