Anti-CD135 Monoclonal Antibody (Clone:BV10A4)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2275-100TESTS
Über dieses Produkt
- SKU:
- 30-2275
- Zusätzliche Namen:
- FLT3||CD135||FLK2||STK1
- translate.label.attr.clone:
- BV10A4
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD135 / FLT3; also known as FLK2 or STK-1 is a receptor tyrosine kinase that plays important roles in hematopoiesis. After binding of Flt3 ligand (FL); CD135 homodimerizes and stimulates proliferation; differentiation and protects the cell from apoptosis. The loss of CD90 and gain of CD135 expression marks the loss of self-renewal in hematopoietic stem cell population. Detectable CD135 expression appears first at low levels on the surface of primitive multilineage progenitor cells and disappears during defined stages of B-cell development; but is upregulated and maintained during maturation of monocytes. CD135 is also expressed on thymocytes; dendritic cell progenitors and on mature dendritic cells; as well as on various malignant hematopoietic cells.
- Host:
- Mouse
- Immunogen:
- BV-173 leukemic cell line
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php