Anti-CD264 / TRAIL-R4 Monoclonal Antibody (Clone:TRAIL-R4-01)-PE Conjugated
Produktgrößen
0.1 mg
£738,00
30-2253-0.1MG
Über dieses Produkt
- SKU:
- 30-2253
- Zusätzliche Namen:
- TNFRSF10D||DCR2||TRAILR4||TRUNDD||UNQ251/PRO288
- translate.label.attr.clone:
- TRAIL-R4-01
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- TRAIL-R4 (CD264; TR4; DcR2; TRUNDD); expressed mainly on CD8+ and NK cells; belongs to receptors of TRAIL; a TNF-like membrane toxic protein that induces apoptosis in many tumour cells; but not in normal cells. TRAIL-R4; however; contains partially truncated death domain; thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).
- Host:
- Mouse
- Immunogen:
- TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg