Anti-CD45R0 Monoclonal Antibody (Clone:UCHL1)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2245-100TESTS
Über dieses Produkt
- SKU:
- 30-2245
- translate.label.attr.clone:
- UCHL1
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD45R0 is the shortest isoform of a receptor-type protein tyrosine phosphatase; CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling; serving as an important regulator of Src-family kinases; promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains; whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages; CD8+ T cells; activated T cells and myeloma cells.
- Host:
- Mouse
- Immunogen:
- Human IL-2 dependent T cells
- Isotyp:
- Mouse IgG2a
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg