Anti-CD40 Monoclonal Antibody (Clone:HI40a)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2229-100TESTS
Über dieses Produkt
- SKU:
- 30-2229
- Zusätzliche Namen:
- B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40
- translate.label.attr.clone:
- HI40a
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types; such as B cells; monocytes/macrophages; dendritic cells; endothelial cells; fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules.
- Host:
- Mouse
- Immunogen:
- Human CD40a
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg