Anti-CD72 Monoclonal Antibody (Clone:3F3)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2201-100TESTS
Über dieses Produkt
- SKU:
- 30-2201
- Zusätzliche Namen:
- CD72
- translate.label.attr.clone:
- 3F3
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells; but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs); CD72 interacts with tyrosine phosphatase SHP-1; thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72; thus enables B cell activation.
- Host:
- Mouse
- Immunogen:
- Normal human lymphocytes from a lymph node.
- Isotyp:
- Mouse IgG2b
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg