Anti-CD22 Monoclonal Antibody (Clone:MEM-01)-PE Conjugated
Produktgrößen
100 tests
£620,00
30-2186-100TESTS
Über dieses Produkt
- SKU:
- 30-2186
- Zusätzliche Namen:
- CD22||SIGLEC2
- translate.label.attr.clone:
- MEM-01
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD22; also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2;6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs); thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.
- Host:
- Mouse
- Immunogen:
- Raji Burkitt's lymphoma cell line
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg