PE Conjugated; Anti-CD114 / G-CSFR Monoclonal Antibody (Clone:LMM741)
Produktgrößen
100 tests
£649,00
30-2131-100TESTS
Über dieses Produkt
- SKU:
- 30-2131
- Zusätzliche Namen:
- CSF3R||GCSFR
- translate.label.attr.clone:
- LMM741
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- CD114 / G-CSFR (granulocyte colony-stimulating factor receptor; also known as CSF3R) is a type I transmembrane glycoprotein which upon binding of its ligand (G-CSF; granulocyte colony-stimulating factor) homodimerizes and activates signaling transduction to mediate cell proliferation; survival; and differentiation. It is expressed by granulocytes at all stages of their differentiation; as well as by monocytes; dendritic cells; and mature platelets. Among non-hematopoietic cells; it is expressed e.g. by endothelial cells; placenta; trophoblasts; and many tumor cell lines. This antigen is a target for stem cell mobilization for blood stem cell transplantation; for enhancing recovery of myelopoiesis following chemotherapy and in the treatment of patients with severe chronic neutropenia.
- Host:
- Mouse
- Immunogen:
- CHO cells transfected with human CD114
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg