Anti-CD79b Monoclonal Antibody (Clone:CB3-1)-FITC Conjugated
Produktgrößen
100 tests
£581,00
30-2089-100TESTS
Über dieses Produkt
- SKU:
- 30-2089
- Zusätzliche Namen:
- CD79B||B29||IGB
- translate.label.attr.clone:
- CB3-1
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- CD79b (Ig beta; B29) forms disulfide-linked heterodimer with CD79a (Ig alpha; MB1). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs); and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently; in pre-B cells; CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. CD79a/b complex interacts with Src-family tyrosine kinase Lyn; which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.
- Host:
- Mouse
- Immunogen:
- Fraction of Ig-associated molecules isolated from Ramos B cells
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg