Anti-CD8b Monoclonal Antibody (Clone:341)-FITC Conjugated
Produktgrößen
0.1 mg
£561,00
30-2073-0.1MG
Über dieses Produkt
- SKU:
- 30-2073
- Zusätzliche Namen:
- Cd8b; Cd8b1; CD8 antigen 37 kDa chain; OX-8 membrane antigen
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- The CD8b (CD8 beta) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells; intraepithelial lymphocytes; NK cells; macrophages; mast cells; and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8; thereby affecting the functional diversity of the TCR signaling.
- Host:
- Mouse
- Immunogen:
- CD8 positive Wistar rat splenic T cell hybridomas
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php