Anti-CD314 Monoclonal Antibody (Clone:1D11)-FITC Conjugated
Produktgrößen
100 tests
£581,00
30-2069-100TESTS
Über dieses Produkt
- SKU:
- 30-2069
- Zusätzliche Namen:
- KLRK1; D12S2489E; NKG2D
- translate.label.attr.clone:
- 1D11
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- CD314; also known as NKG2D (natural killer receptor G2D) or KLRK1 (killer cell lectin-like receptor subfamily K; member 1); is a homodimeric C-type lectin-like activating receptor and costimulator with type II membrane orientation (C teminus extracellular). CD314 homodimers are associated with DAP10; a membrane adaptor protein that signals similar to CD28 by recruitment of phosphatidylinositol 3-kinase. Engagement of CD314 amplifies antigen-specific T cell responses in CD314-positive T cell populations. In NK cells; CD314 is a primary activating receptor. As CD314 ligands the MHC class-I chain-related proteins A and B (MICA; MICB) and UL16-binding proteins (ULBPs) have been identified.
- Host:
- Mouse
- Immunogen:
- NKL cell line
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg