Anti-CD154 / CD40L Monoclonal Antibody (Clone:MR-1)-FITC Conjugated
Produktgrößen
0.1 mg
£551,00
30-2061-0.1MG
Über dieses Produkt
- SKU:
- 30-2061
- Zusätzliche Namen:
- Cd40lg||Cd40l||Tnfsf5
- translate.label.attr.clone:
- MR-1
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family; and is expressed primarily on activated CD4+ lymphocytes; but also on mast cells; basophils; eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells; including dendritic cells; macrophages; and B cells; and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
- Host:
- Hamster
- Immunogen:
- Activated mouse Th1 clone D1.6
- Isotyp:
- Hamster IgG1
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php